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KMID : 0104920170260010001
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Journal of Hawhwa Medicine
2017 Volume.26 No. 1 p.1 ~ p.10
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A Survey on Ancient Literature Records on Woohwangchungsim-won and its potential clincial application
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Oh Young-Taeck
Oh Hyeon-Muk
Kim Seo-Woo
Kim Won-Yong
Son Chang-Gue
Cho Jung-Hyo
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Abstract
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Objectives: The aim of this study is ① to investigate the historic changes and pharmacological efficacies of Woohwangchungsim-won and ② to discuss the necessities for Woohwangchungsim-won’s clinical applications.
Methods: This study was performed through ① investigating the ancient literature records related with Woohwangchungsim-won and analyzing Woohwangchungsim-won’s composition, dosage and indications, ② searching articles about Woohwangchungsim-won on 10 major Korean web and 3 major foreign web article search engines and analyzing Woohwangchungsim-won’s pharmacological efficacies and indications.
Results: Woohwangchungsim-wom has been used for cerebrovascular diseases such as stroke and palpitation. Also, there are some ancient literature records of Woohwangchungsim-won's clinical applications in neuropsychiatric disorders
such as depression and bipolar disorder. In addition, there have been a number of experimental studies which demonstrate Woohwangchungsim-won's neuroprotective effect on cerebral cortex and hippocampus injury. So, it is possible to infer that Woohwangchungsim-won can be used for the treatments of neuropsychiatric disorders associated with neuronal cell death in cerebral cortex and hippocampus. But there have been no or less experimental studies which demonstrate the pharmacological efficacy of Woohwangchungsim-won on such disease.
Conclusion: It is necessary that further experimental studies which demonstrate Woohwangchungsim-won's pharmacological efficacy on neuropsychiatric disorders should be done and Woohwangchungsim-won's clinical applications should be expanded on the basis of those related experimental results.
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KEYWORD
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Woohwangchungsim-won, History of Changes, Experimental Studies, Clinical Application
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